The safe contains the Nuka-Cola Clear formula plus some random minor loot. There is an R&D safe here, that can be unlocked only with a key that is in possession of Milo, shipping foreman. The terminals here contain some info on development of the Nuka-Cola Quantum and the difficulties (or rather casualties) that occurred in the process. Look up at the ceiling immediately after entering the lobby to see a hole and part of a filing cabinet with a Chinese Army: Special Ops Training Manual in it. The first section of the factory contains the R&D department (the cells name 'Factory Floor' refers to the part beyond the locked door). The building is divided into four sections: Research and development, storage and mixing vats, offices, and factory floor.
2.1 Factory floor (before passing locked door).